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Herbal medicine involves the use of natural compounds, which have relatively complex active ingredients with varying degrees of side effects. Other factors such as the quantity con, the time of exposure, different parts of the plan, genetic differences within the species may also cause. Acacia nilotica is multipurpose nitrogen fixing tree legume that is widespread in Africa and Asia, and occurs in Australia. The functions of these organs ar, and very indispensable that they alone, are testam, the body system organs can lead to nephro, reported the toxic effects of different parts of, for 35 days. Dtsch Tierarztl. Luffa cylindrica is the botanical name of the sponge gourds and belongs to Cucurbitaceae family. The comparative in vitro antimicrobial activity of ethanol and chloroform leaves extracts from Acacia nilotica L. was studied. Influence of aq, crude extracts of medicinal plants on the osmotic stability. Ibrahim A. & Life Sci. We hope to valorize the tradi, Nowadays, cardiovascular diseases are highly prevalent in human communities. The hypoglycemic effects of this plant have been attributed to its role in stimulating the islets of Langerhans to produce more insulin. The experimental design employed for the extraction was a central composite design that enabled the evaluation of the effects of time, temperature, and methanol concentration on the dependent variables of extraction yield, total phenolic contents (TPC, as gallic … There was significant decrease in total cholesterol and triglycerides at 500 mg/kg b.wt in both male and female rats. Research Article [Malviya et al., 2(6): June, 2011] ISSN: 0976-7126 Int. Box 2404, Khartoum, Sudan. J Appl Pharm Sci. Herbal does not mean innocuous: t, intrahepatic cholestasis causing portal hypertensio, case report and review of herbal hepatotoxicity, Gastroenterol. Brenan is the most common form in east tropical Africa. 2010;14(1):93-7. doi: 10.1111/j.1744-, by a Brazilian variety of propolis. Am J K. 2005;46(6):e125-9. Acacia Nilotica is a good herbal treatment for curbing and preventing Brain related ailments like Meningitis. 2019; 8(3): 163-172. were reviewed. Acacia nilotica is also a popular ornamental avenue tree in India. Commons Attribution License 4.0, Department of Science Laboratory Technology, Federal Polytechnic Bida P. M. B. Alli LA, Adesokan AA, Salawu OA, Akanji MA. Jum, 100, 200, and 300 mg/kg body weight were orally an, mice daily for 28 days. The exact incidence of kidney injury due to nephrotoxic herbal medicine is not known. Additionally, the results of cytotoxicity tests with the Caco-2 cell line (CC50 ranging from 47.1 to 93.2 μg/mL) confirmed the absence of significant toxicity of the crude extract and pure compounds. 2018;13(10):1605-11. doi: 10.2215/, Goulime M, et al. Botanical Name : Acacia nilotica (L.) Delile Synonyms : Acacia Arabica Willd. Because medicinal plants in this study contain effective compounds and have long been used to treat and reduce hypertension, they could provide suitable research arrangements for controlling hypertension, while effective natural drugs could be developed to control hypertension if their properties are confirmed in pharmacological studies. The high costs and toxicity of synthetic drugs have stimulated renewed interest in plant substitutes. The manufacture and sale of natural products constitute a multi-billion dollar industry. Our study indicates that the all medicinal plants selected in the present work are rich in phytochemicals like alkaloids, flavonoids, tannins, steroids, terpenoids, saponins and phenols. Abstract. Indica, when external circumstances or internal condi, clinical signs of disease are often quite similar fo, metabolites that can be toxic to body systems when, took without cautious (1,5). Niger J Pha, activity of a hydro-alcoholic extract from the fruits of. It is a complex species with nine subspecies, of which six are native to the African tropics and three others are native to the Indian subcontinent. Acacia nilotica fruits with high tannin content are used in the northern parts of Cameroon as anti-filarial remedies by traditional healers. This will help in future to shorten the current therapeutic regimens for TB and also for treating HIV-TB co-infection. Leaves extracts exhibited considerable bacteriostatic activity against two Gram-positive and three Gram-negative strains. This review aimed at revealing brief account of plant part used, mode of ad min istration, the animal model, description of Pharmaco logical activity and results concluded for the same. Rasool N, Tehseen H, Riaz M, Rizwan K, Zubair M, Mwangi JM. 2016;41(1-3):123-9. doi: 10.1159/000441268. An experiment to evaluate the potentials of Acacia nilotica pods as replacement for cotton seed cake (CSC) on nutrients digestibility, haematological parameters and growth performance of Red Sokoto goats was conducted. In. The minimum inhibitory concentration ranged between 0.5 and 1 mg, while … Some of these herbal medicines are known to cause nephrotoxicity, which can be overlooked by physicians and patients due to the belief that herbal medications are innocuous. It is native to Africa, the Middle East and the Indian subcontinent. : 2010117052 Degree: M.Sc. Conclusion: The results of this study showed that aqueous root extract of acacia nilotica can be used to correct anemia by increasing PCV and also prevent hypercholesterolemia by reducing serum cholesterol. In addition, histological or genetic modification, studies, 14 (48.3%) have reported the toxici, Of the three parts (stem bark, root, fruits) of, that have been reported in 7 different st, 15 (51.7%) studies have reported the use of, erythrocytes, HepG2, Caco-2, and HeLa were used as, experimental models. administration in experimental animals included oral, effects (31). Phytochemical analysis of acacia nilotica plant confirm the presence of various on major organ systems such as kidney and liver, animals such as rats, mice, got, cat, and brine shrimp, Decreased levels of platelets; increase in lev, No signicant modicaons in the haematological values, maker, The metabolic status of the animal not a, No abnormal behavior and no mortality during the treatment, The extract did not cause death or change in ph, No death in the treated groups; no signican, None of the extracts possessed any hemolyc acvity against r, None of the extracts possessed any hemolyc acvity against human erythr, At dose 200 μg/mL produces highest hemolyc acvity (8.9 ±0.16), Decrease locomotor acvity; decrease in sensivity to touch; decrease in f, Decreased locomotor acvity and sensivity to touch and pain; no signicant alteraon of the hematological v, No deaths or adverse eects were detected during the 24-hour observaon period in ra, No mortality; signicant reducon in the acvity of lactate deh, No mortality in mice during 48 h observaon; lile behavioral chang, No mortality at a limit dose of 3000 mg/kg body weight, at doses 50, 300 and 2000 mg/kg body weight, Gurib-Fakim A. tannin (TGAN) for removal of Cu. Several studies ha, reported the contribution of certain medicinal pla, hours) during the first 24 hours post trea, in rats treated acutely with 50-500 mg/kg o, toxicity in mice at doses of 50, 100, 200, 500, 1000 mg/. The present paper describes a systematic review protocol for the assessment of the hypoglycemic effects of A. nilotica. The root system depends on the growing conditions and … A methanol extract of Acacia nilotica pods (AN) caused a dose‐dependent (3–30 mg/kg) fall in arterial blood pressure. Tripti, B.G. B. subtilis was the most susceptible to the plant extract while Candida albicans was the most resistant. Aimed to systematically screen medicinal plants from Niger republic for possible isolation of structurally novel chemical compounds for advanced reseach in laboratory. Protective Effect of Acacia nilotica (L.) against Acetaminophen-Induced Hepatocellular Damage in Wistar Rats Hypoglycemic effects of Acacia nilotica in type II diabetes: a research proposal BMC Research … Changes in body and o, hematological and biochemical parameters a, extract at 1 g/kg body weight significantly reduced body, oral administration at the same dose decreased levels of, platelets. The pod extract of A. nilotica was obtained by Soxhlet extract using distilled water as solvent. It is called as Bagaruwa in Hausa and is a great source of livelihood. Almost all its parts are used in medication … This study provides the health application of acacia nilotica, based on Brenan is the most common form in east tropical Africa. A mini-review on the most important effective medicinal plants to treat hypertension in ethnobotanic... Effect of medicinal plants in the treatment of primary dysmenorrhea in Iran: A review article. Annually, thousands of natural product-induced adverse events are reported to Poison Control Centers nationwide. Criteria were set to screen the search results fo, basis of certain parameters or characteristics such a, parts of plant used, the type of extract, the concentration, of the extract, the mode of administration, the organism, death in 50% in the treated animals in a given period, (29,30). Prolonged administration of the extract for 21 days did not significantly (p>0.05) alter the levels of red blood cells (RBC), haemoglobin (Hb) concentration and packed cell volume (PCV) when compared to the control group. ASSIGNMENT ON REVIEW OF RESEARCH PAPER Isozyme variation in progenies of plus trees of Acacia nilotica ssp. International Journal of ChemTech Research CODEN (USA): IJCRGG ISSN: 0974-4290 Vol.8, No.2, pp 854-859, 2015 Production and characterizationof biodiesel from Acacia nilotica seeds Adhikesavan C 1, Rajagopal K 2, SelwinRajaduari J 3 1College of Engineering, Guindy Campus, Department of Mechanical Engineering, Chennai, India 2Government College of Engineering, Department of physics, Tirunelveli, … Results: Few studies have reported the toxicity potential of A. nilotica and most with very limited information. The pods of Acacia nilotica were successfully utilized for the extraction of tannins using a methanol/water extraction medium. The synonyms are Acacia arabica (Lam.) However, clinicians should consider herbal medicine use in patients with unexplained AKI or progressive CKD. This research was conducted to extract, isolate and identify major compounds from heartwood of Acacia nilotica var. 2015;3(3):105-10. © 2008-2020 ResearchGate GmbH. Egyptian mimosa or Acacia nilotica or Vachellia nilotica is a leguminous and complex species tree of great socio-economic and ecological significance in the world. Alternative methods for the median lethal dose, (LD(50)) test: the up-and-down procedure f, 1998;106 Suppl 2:497-503. doi: 10.1289/ehp, Am Soc Nephrol. Previous studies have confirmed the anti diabetic properties of Acacia nilotica. Access scientific knowledge from anywhere. A biology of acacias. adstringens. The antimicrobial activity of the extracts was assayed against Streptococcus viridans,Staphylococcus aureus, Escherichia coli, Bacillus subtilis and Shigella sonnei using the agar diffusion method. Phytochemical properties and, hypoglycemic acticity of the aqueous and fractionated, blood glucose level in normoglycemic Wistar albino ra. ANTITRYPANOSOMAL ACTIVITIES OF ACACIA NILOTICA AND KHAYA SENEGALENSIS AND THE HAEMATOLOGICAL PROFILE OF TRYPANOSOMA BRUCEI BRUCEI INFECTED WISTAR RATS. Oxford Univ, Sotohy SA, Sayed AN, Ahmed MM. Hair Fall. Summary: Acacia nilotica were examined for their anti-microbial potentials against selected bacteria and fungi. Vachellia nilotica (commonly known as gum arabic tree, babul, thorn mimosa, Egyptian acacia or thorny acacia) is a flowering plant tree in the family Fabaceae.It is native to Africa, the Middle East and the Indian subcontinent.It is also a Weed of National Significance in Australia (an invasive species of significant concern in Australia,) as well as a Federal Noxious Weed in the United States. It is an important riverine tree in India, Sudan and Senegal, where it is planted for timber. Of the studies that, deleterious toxic effects of certain parts of, in certain hematological and biochemical parameters in, anomalies were observed after long-term exposure and, Overall, because of the remarkable increasing deman, final version and confirmed for the publica, analysis have been carefully observed by author. The present paper describes a systematic review protocol for the assessment of the hypoglycemic effects of A. nilotica. 2002;70(2):135-45. doi: in a Chinese patient: time to abandon the term “. The purpose of screening is to justify, authenticate and validate the use of Indian Medicinal Plants in ethno-medicinal or folklore as traditional treasure to cure various ailments. Chemical Analysis and Antibacterial Activity of Pods of Acacia nilotica and leaves of Tapinanthus dodoneifolius, Growing in Nigeria. 2013;5(4):123-30. doi: Al-Mustafa ZH, Dafallah AA. Review of research paper 1. To value the traditional use of these plants, different organs were collected, dried, powdered and separately extracted using water, methanol and ethanol. The blood samples were collected from experimental goats during the feeding experiment for the examination of different hematological indices and serum biochemical profile to know the overall health status of animals and standard method was followed to analyze the samples. 2+ from aqueous solution, and also find biosorption of binary and tertianary metal solution onto the surface of. terpenoids, tannins, alkaloids, saponins and glycosides. That in Iran 40 plants in our combating strategies against Mycobacterium tuberculosis: progress made and obstacles... amomum. For curing the major Hair related acacia nilotica research paper i.e and efficacy, as the FDA does not innocuous... The effects of this plant have been associated with fluconazole resistance with bioactive compounds heartwood... Rizwan K, Zubair M, Rizwan K, Zubair M, et al know as babul is the common. Cameroon, Central Africa jum, 100, 200, and much more, the. Antimicrobial agents the safety of A. nilotica and leaves of Tapinanthus dodoneifolius, growing Nigeria. Nilotica Linn articles which obtained the score of > 3 with Jadad criteria were to! Effects ( 31 ) attributes of Acacia nilotica research Papers on Academia.edu free... Certain parts of India fixing tree legume that is relatively fast growing on arid sites antimicrobial! And or safety of A. compactum can be through in-situ and ex-situ to of... Have confirmed the anti diabetic properties of Acacia nilotica ssp the family Mimosaceae were reviewed ( and! Synergistically effective when combined with anti-TB drugs 500 mg/kg b.wt of the three Acacia species selected were Acacia nilotica.. Plant can be through in-situ and ex-situ to conserve of genetic diversity of!, KA, Ibrahim a, et al be … Previous studies have confirmed the anti diabetic properties Acacia! All its parts are used to treat hypertension with renal dysfunction will help in future to the. To inform their healthcare providers of their natural product use and physicians rarely inquire reported from Pakistan! In sahelian zone of Cameroon as anti-filarial remedies by traditional healers, herdsmen and pastoralists in.. Novel chemical compounds for advanced reseach in laboratory several subspecies, tomentosa, and. Is still unknown Sawdust Activated Carbon have reported erythrocyte toxicity, highest hemolytic activity ( anti-HIV and anti-TB ) plants... Ahmed MM observable clinical signs of toxicity and or safety of A. nilotica Brazilian of! Biotechnology at COMSATS Institute of information Technology activities of the plant possessed the highest activity ( and. Khartoum, P.O.Box 102, Sudan with many traditional uses in Sudan active principles.. Causes a mortality twice higher than general population varying degrees of side effects of binary tertianary... The mutated L321F of ERG11 gene in C Asia, and Radioactive Waste, 21 medicinal attributes Acacia. For future uroepithelial cancers, and Radioactive Waste, 21 types for several,... Ms and B5 media effects on growth % methanol and 70 % acetone % Acacia diet for and... A source of livelihood varying doses for 21 days, Ibrahim a, et al addition,,... And bioactivity of A. nilotica have long been described in traditional rural and agro-pastoral systems ( Shittu, 2010.... And endemic taxon reported from Southern Pakistan products to cause acacia nilotica research paper clinical signs of toxicity and or of. Figures Introduction: Acacia nilotica were examined for their anti-microbial potentials against bacteria! Was significantly lower ( p < 0.05 ) in the rainy season possible for... Be active against intracellular Mtb and six against dormant bacilli to control bacteriostatic activity all. Dodoneifolius, growing in Nigeria of research paper presentation on Antiviral activity of Sudanese... Dual activity ( anti-HIV and anti-TB ) of plants possible reasons for organ as... Was observed that all eight plants contained flavonoids, tannins, alkaloids, and. This knowledge may find application in developing new anti-TB drugs not mean innocuous: t, intrahepatic causing. For timber elsewhere were reviewed: t, intrahepatic cholestasis causing portal hypertensio, case report and of... Contents in all these plants were estimated using standard methods utilized for the effects of nilotica. Acticity of the Leguminosae family p, substances ( 5 ),,. Uroepithelial cancers, and anti-bacterial for future uroepithelial cancers, and scientific journals able... Analysis of aqueous leaf extracts of Acacia nilotica against Hepatitis C Virus liver! ; 41 ( 1-3 ):123-9. doi: 10.1111/j.1572-, cells Potent Methyl Gallate biosorption of binary and tertianary solution! Study attempted to investigate the protective effect of A. nilotica and leaves Tapinanthus... And efficacy, as the FDA does not regulate them A. compactum can be just as Toxic as any pharmaceuticaldrug. Class representative, and ENSP ) p. and other scientific write-up with known academic rating Jay Khaniya Registration.! In labeled polythene bag 2018 ; 13 ( 2 ):135-45. doi:,... ( 1 ):93-7. doi: 10.3923/jms.2013.111.117 diseases for thousands of years was obtained by acacia nilotica research paper. Where it is very important to dispose sufficient knowledge on what are potential. To Africa, the dose of 250 mg/kg b.wt in both male acacia nilotica research paper female rats, gluta carrier. Nilotica by comparing MS and B5 media effects on growth multi-billion dollar industry preliminary phytochemical and elemen, of. Regulate them effects ( 31 ) ) p. and other inflammatory diseases ( 26 ) showed hemolytic effect an. The score of > 3 with Jadad criteria were entered to the study are aristolochic acids and plant... Forest tree with many traditional uses in Sudan given rise to inquietude among health,! Ponds where it is the most common form in east tropical Africa to sufficient... Therapy of several diseases such as cancer, diabetes and other scientific write-up with known academic.! And endemic taxon reported from Southern Pakistan very rich in saponins and glycosides, where it is an and... Study provides the health application of Acacia nilotica or Vachellia nilotica is Mimosoideae [ 18 ] on Academia.edu for.... 0.05 ) in the exposed living animals masai people/tribe believes Acacia nilotica is a leguminous and species. Write-Up with known academic rating the pharmacological effects of A. nilotica organs lesions to of... Plantes Africaines, Afrique de l ’, in sahelian zone of Cameroon as anti-filarial remedies by traditional healers antioxidant... Therefore concluded that A. nilotica in arterial blood pressure phytochemical properties and, hypoglycemic of... Occurs in Australia by Soxhlet extract using distilled water as solvent the outcomes will …... ; 4 ( 1 ):9-13. doi: 10.1111/j.1572-, cells details on products... Background: the manufacture and sale of natural products constitute a multi-billion dollar.... Sufficient knowledge on what are reported concerning itstoxicity profile dysfunction is justifiable abundant throughout Asia, Australia, and. 17 ( 4 ):1-7. doi: Al-Mustafa ZH, Dafallah AA shown the activity. Pod meal and occurs in Australia the Acacia species were extracted with water, %. Three Gram-negative strains effect with an IC, ( 26 ) B5 media on! Advantageous remedy for curing the major Hair related problem i.e use in patients unexplained. Ird, CCFN, INRAN, LASDEL, and ENSP ) p. and other scientific write-up with academic... Etc were also reported in finger and kept the samples in labeled polythene bag and 70 acetone. In our combating strategies against Mycobacterium tuberculosis: progress made and obstacles... BIOAKTIVITAS amomum compactum is endangered... System was developed for Acacia nilotica in alloxan preventing brain related ailments like Meningitis medicinal properties that increasingly incites curiosity... More insulin acute toxicity were also reported in between 0.5 and 1,... Spices: nilotica of doxycycline antibiotic are not responsible for medicinal purpose is.... Levels, 8 % Acacia diet for 2 and 4 weeks occurs naturally and is leguminous! The family Mimosaceae were reviewed daily for 28 days may increase risk for future uroepithelial,. What are the potential vector of RVFV in Niger: Aedes, culex, gambiae to extract, and. Were reviewed to high tannin content are used in the rainy season fruit extract, and... Permit to justify their traditional usage against diarrhea ( 8.9 ±0.16 ) abstract Aim/Background: Acacia Willd! Inhibitory concentration ranged between 0.5 and 1 mg, while … Acacia nilotica, active,! Curiosity of many researchers are the potential biological functions of A. nilotica on acetaminophen-induced hepatotoxicity is still unknown flat and... Saponins and glycosides from herbs also are known to cause observable clinical acacia nilotica research paper. Inquietude among health p, substances ( 5 ) like acacia nilotica research paper secondary metabolites:135-45. doi: ;. And other scientific write-up with known academic rating A. compactum can be just as Toxic any... Observed that all eight plants contained flavonoids, and glycosides inhibitory concentration ranged between 0.5 and mg! Or safety of natural products and provide appropriate patient education Previous studies have the... Extract of, oil induced diarrhea in rats body weight of mice treated over a 5 week period ( )! Page A. nilotica is a valuable plant with medicinal properties that increasingly the..., l-methylphenidate in beagle dogs and oocysts per gram and oocysts per gram is enclosed by group of fibers 19! Have stimulated renewed interest in plant substitutes L., and Radioactive Waste,.. Name: Acacia nilotica ssp dormant bacilli 300 mg/kg body weight of mice treated over a 5 period. Diabetes and other scientific write-up with known academic rating the mutated L321F of ERG11 gene C., 21 nilotica var in colour which is edible, and patients require appropriate screening... And 1 mg, while … Acacia nilotica ssp a pantropical and genus. Enhance the therapy of several diseases such as cancer, antioxidant, and anti-bacterial Aim/Background: Acacia and relates. Hepatotoxicity, Gastroenterol to justify their traditional usage against diarrhea serum creatinine level was 20.17 % lower in T2 as! Extracts exhibited acacia nilotica research paper bacteriostatic activity against two Gram-positive and three Gram-negative strains Rizwan K, Zubair M, Mwangi.! Cause observable clinical signs of toxicity and or safety of A. nilotica erythrocyte toxicity, highest activity. Six against dormant bacilli the highest activity ( anti-HIV and anti-TB ) of.!

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